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Biotech/pharma These sub-industries have been a market favorite for some time, which can make it challenging to find stocks with attractive valuations. Investors in this category must also contend with the possibility of binary outcomes, as a biotech or drug company can either see its share price soar if its drug receives FDA approval or plummet if approval is denied. Yet we believe it is worth investing in biotech pharma because of the high growth potential of many of these companies. We think we are able to navigate successfully around the potential pitfalls of bio-pharma investing because of our in-depth understanding of the FDA approval process and the science behind pharmaceutical compounds. Our general focus in this space is on companies with either approved drugs or large pipelines addressing multi-billion dollar clinical market opportunities. Examples include TherapeuticsMD, Inc., which makes hormone replacement drugs for menopause and other conditions, and Flexion Therapeutics Inc., which makes long lasting injectable pain relief drugs for arthritis. Other companies we favor have wrapped intellectual property around an already proven pharmaceutical to create a new, protected franchise. The risk of not receiving approval for such products is significantly lower than for a typical bio-pharma investment. An example is Pacira Pharmaceuticals, Inc. ( PCRX ), whose FDA-approved medication is comprised of the pain killer bupivacaine combined with proprietary IP called Depo-Foam that enables its timed release. The product is appealing as it can in many cases eliminate the need for post-operative opiates and result in a shorter hospital stay.
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